Oxidative Stress Reduction

EGCG:              EGCG was found to be the most effective of the green tea catechins in scavenging superoxide anions and hydroxyl radicals[1], two reactive oxygen species (ROS) implicated in oxidative stress imbalances. The results demonstrated that one molecule of EGCG is capable of trapping ~ 10 molecules of both superoxide anions and hydroxyl radicals.

The antioxidant and pro-oxidant effect of EGCG was investigated in a study[2] involving the comparative scavenging effects of EGCG and ascorbic acid versus superoxide anion. The effects of EGCG on free radical-induced DNA oxidative damage was nox app player pokemon go also investigated. The results demonstrated that EGCG scavenged superoxide radical and hydrogen peroxide in a dose dependent manner and that EGCG had a stronger scavenging activity than ascorbic acid. Results also showed that EGCG had a protective effect on DNA at low concentrations but enhanced oxidative damage at higher concentrations.

 

 

 


[1] Nanjo F et al (1999) Radical scavenging activity of tea catechins and their related compounds. Bioscience Biotechnology and Biochemistry 63(9)1621-1623.

[2] Tian B et al (2007) Chemiluminescence analysis of the prooxidant and antioxidant effects of epigallocatechin-3-gallate. Asia Pacific Journal of Clinical Nutrition 16(Supplement 1):153-157.

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