Clinical Evidence scFOS

ScFOS:             A double-blind, placebo-controlled study[1] was performed in the medical departments of five hospitals to study the effects of regular consumption of scFOS on the digestive comfort of subjects with minor functional bowel disorders (FBD). A total of 105 subjects agreed to take part in the study and asked to complete a questionnaire related to symptoms such as abdominal discomfort or pain; abdominal fullness, bloating or swelling; feeling of incomplete bowel movement; urgency, i.e. an imperious urge to pass stool; straining at stool. Subjects also indicated intensity on a scale from 1 to 10 (10 being the maximum intensity level).

The results (image below) demonstrated that 6-week consumption of 2 x 2.5 g scFOS per day led to a decrease in the intensity of digestive disorders and abdominal pain in which the latter was significantly lower (p = 0.026) when compared with the placebo maltodextrin (open circles represent scFOS and closed circles placebo). Improvement was also noted in digestive comfort in subjects with minor FBD, thereby improving quality of life as well as social performance.


The authors did comment that “in the present study, the placebo effect appeared remarkably high”.


[1] Paineau D et al (2008) The effects of regular consumption of short-chain fructo-oligosaccharides on digestive comfort of subjects with minor functional bowel disorders. British Journal of Nutrition 99:311-318

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